Electronic circuit analog of synthetic genetic networks: Revisited
نویسندگان
چکیده
منابع مشابه
An Electronic Analog of Synthetic Genetic Networks
An electronic analog of a synthetic genetic network known as the repressilator is proposed. The repressilator is a synthetic biological clock consisting of a cyclic inhibitory network of three negative regulatory genes which produces oscillations in the expressed protein concentrations. Compared to previous circuit analogs of the repressilator, the circuit here takes into account more accuratel...
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We propose the use of nonlinear electronic circuits to study synthetic gene regulation networks. Specifically, we have designed two electronic versions of a synthetic genetic clock, known as the “repressilator,” making use of appropriate electronic elements linked in the same way as the original biochemical system. We study the effects of coupling in a population of electronic repressilators, w...
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We report the experimental verification of noise-enhanced logic behaviour in an electronic analog of a synthetic genetic network, composed of two repressors and two constitutive promoters. We observe good agreement between circuit measurements and numerical prediction, with the circuit allowing for robust logic operations in an optimal window of noise. Namely, the input-output characteristics o...
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ژورنال
عنوان ژورنال: The European Physical Journal Special Topics
سال: 2017
ISSN: 1951-6355,1951-6401
DOI: 10.1140/epjst/e2016-60396-5